Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model

Reduced dietary protein intake and intermittent fasting (IF) are both linked to healthy longevity in rodents, and are effective in inhibiting cancer growth. The molecular mechanisms underlying the beneficial effects of chronic protein restriction (PR) and IF are unclear, but may be mediated in part...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lamming, Dudley W., Cummings, Nicole E., Rastelli, Antonella L., Gao, Feng, Cava, Edda, Bertozzi, Beatrice, Spelta, Francesco, Pili, Roberto, Fontana, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741600/
https://ncbi.nlm.nih.gov/pubmed/26378060
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