JAK2 tyrosine kinase mediates integrin activation induced by CXCL12 in B-cell chronic lymphocytic leukemia

Chemokines participate to B-cell chronic lymphocytic leukemia (B-CLL) pathogenesis by promoting cell adhesion and survival in bone marrow stromal niches and mediating cell dissemination to secondary lymphoid organs. In this study we investigated the role of JAK protein tyrosine kinases (PTK) in adhe...

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Foilsithe in:Oncotarget
Main Authors: Montresor, Alessio, Toffali, Lara, Mirenda, Michela, Rigo, Antonella, Vinante, Fabrizio, Laudanna, Carlo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2015
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741449/
https://ncbi.nlm.nih.gov/pubmed/26413812
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