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JAK2 tyrosine kinase mediates integrin activation induced by CXCL12 in B-cell chronic lymphocytic leukemia

Chemokines participate to B-cell chronic lymphocytic leukemia (B-CLL) pathogenesis by promoting cell adhesion and survival in bone marrow stromal niches and mediating cell dissemination to secondary lymphoid organs. In this study we investigated the role of JAK protein tyrosine kinases (PTK) in adhe...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Montresor, Alessio, Toffali, Lara, Mirenda, Michela, Rigo, Antonella, Vinante, Fabrizio, Laudanna, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741449/
https://ncbi.nlm.nih.gov/pubmed/26413812
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