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JAK2 tyrosine kinase mediates integrin activation induced by CXCL12 in B-cell chronic lymphocytic leukemia

Chemokines participate to B-cell chronic lymphocytic leukemia (B-CLL) pathogenesis by promoting cell adhesion and survival in bone marrow stromal niches and mediating cell dissemination to secondary lymphoid organs. In this study we investigated the role of JAK protein tyrosine kinases (PTK) in adhe...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Montresor, Alessio, Toffali, Lara, Mirenda, Michela, Rigo, Antonella, Vinante, Fabrizio, Laudanna, Carlo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741449/
https://ncbi.nlm.nih.gov/pubmed/26413812
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