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JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation
Lymphocyte recruitment is regulated by signaling modules based on the activity of Rho and Rap small guanosine triphosphatases that control integrin activation by chemokines. We show that Janus kinase (JAK) protein tyrosine kinases control chemokine-induced LFA-1– and VLA-4–mediated adhesion as well...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871442/ https://ncbi.nlm.nih.gov/pubmed/24368807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303067 |
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