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JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation
Lymphocyte recruitment is regulated by signaling modules based on the activity of Rho and Rap small guanosine triphosphatases that control integrin activation by chemokines. We show that Janus kinase (JAK) protein tyrosine kinases control chemokine-induced LFA-1– and VLA-4–mediated adhesion as well...
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| Главные авторы: | , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871442/ https://ncbi.nlm.nih.gov/pubmed/24368807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303067 |
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