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Cofilin-induced cooperative conformational changes of actin subunits revealed using cofilin-actin fusion protein

To investigate cooperative conformational changes of actin filaments induced by cofilin binding, we engineered a fusion protein made of Dictyostelium cofilin and actin. The filaments of the fusion protein were functionally similar to actin filaments bound with cofilin in that they did not bind rhoda...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Umeki, Nobuhisa, Hirose, Keiko, Uyeda, Taro Q. P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740740/
https://ncbi.nlm.nih.gov/pubmed/26842224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20406
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