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Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy

High-speed atomic force microscopy was employed to observe structural changes in actin filaments induced by cofilin binding. Consistent with previous electron and fluorescence microscopic studies, cofilin formed clusters along actin filaments, where the filaments were 2-nm thicker and the helical pi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ngo, Kien Xuan, Kodera, Noriyuki, Katayama, Eisaku, Ando, Toshio, Uyeda, Taro QP
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337605/
https://ncbi.nlm.nih.gov/pubmed/25642645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04806
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