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Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy

High-speed atomic force microscopy was employed to observe structural changes in actin filaments induced by cofilin binding. Consistent with previous electron and fluorescence microscopic studies, cofilin formed clusters along actin filaments, where the filaments were 2-nm thicker and the helical pi...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Ngo, Kien Xuan, Kodera, Noriyuki, Katayama, Eisaku, Ando, Toshio, Uyeda, Taro QP
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337605/
https://ncbi.nlm.nih.gov/pubmed/25642645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04806
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