Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin

Heavy meromyosin (HMM) of myosin II and cofilin each binds to actin filaments cooperatively and forms clusters along the filaments, but it is unknown whether the two cooperative bindings are correlated and what physiological roles they have. Fluorescence microscopy demonstrated that HMM-GFP and cofi...

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Pubblicato in:Sci Rep
Autori principali: Ngo, Kien Xuan, Umeki, Nobuhisa, Kijima, Saku T., Kodera, Noriyuki, Ueno, Hiroaki, Furutani-Umezu, Nozomi, Nakajima, Jun, Noguchi, Taro Q. P., Nagasaki, Akira, Tokuraku, Kiyotaka, Uyeda, Taro Q. P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071871/
https://ncbi.nlm.nih.gov/pubmed/27762277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35449
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