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Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin

Heavy meromyosin (HMM) of myosin II and cofilin each binds to actin filaments cooperatively and forms clusters along the filaments, but it is unknown whether the two cooperative bindings are correlated and what physiological roles they have. Fluorescence microscopy demonstrated that HMM-GFP and cofi...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Ngo, Kien Xuan, Umeki, Nobuhisa, Kijima, Saku T., Kodera, Noriyuki, Ueno, Hiroaki, Furutani-Umezu, Nozomi, Nakajima, Jun, Noguchi, Taro Q. P., Nagasaki, Akira, Tokuraku, Kiyotaka, Uyeda, Taro Q. P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071871/
https://ncbi.nlm.nih.gov/pubmed/27762277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35449
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