Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin

Heavy meromyosin (HMM) of myosin II and cofilin each binds to actin filaments cooperatively and forms clusters along the filaments, but it is unknown whether the two cooperative bindings are correlated and what physiological roles they have. Fluorescence microscopy demonstrated that HMM-GFP and cofi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ngo, Kien Xuan, Umeki, Nobuhisa, Kijima, Saku T., Kodera, Noriyuki, Ueno, Hiroaki, Furutani-Umezu, Nozomi, Nakajima, Jun, Noguchi, Taro Q. P., Nagasaki, Akira, Tokuraku, Kiyotaka, Uyeda, Taro Q. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071871/
https://ncbi.nlm.nih.gov/pubmed/27762277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35449
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