Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin

Heavy meromyosin (HMM) of myosin II and cofilin each binds to actin filaments cooperatively and forms clusters along the filaments, but it is unknown whether the two cooperative bindings are correlated and what physiological roles they have. Fluorescence microscopy demonstrated that HMM-GFP and cofi...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Ngo, Kien Xuan, Umeki, Nobuhisa, Kijima, Saku T., Kodera, Noriyuki, Ueno, Hiroaki, Furutani-Umezu, Nozomi, Nakajima, Jun, Noguchi, Taro Q. P., Nagasaki, Akira, Tokuraku, Kiyotaka, Uyeda, Taro Q. P.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071871/
https://ncbi.nlm.nih.gov/pubmed/27762277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35449
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