Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin

Heavy meromyosin (HMM) of myosin II and cofilin each binds to actin filaments cooperatively and forms clusters along the filaments, but it is unknown whether the two cooperative bindings are correlated and what physiological roles they have. Fluorescence microscopy demonstrated that HMM-GFP and cofi...

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Vydáno v:Sci Rep
Hlavní autoři: Ngo, Kien Xuan, Umeki, Nobuhisa, Kijima, Saku T., Kodera, Noriyuki, Ueno, Hiroaki, Furutani-Umezu, Nozomi, Nakajima, Jun, Noguchi, Taro Q. P., Nagasaki, Akira, Tokuraku, Kiyotaka, Uyeda, Taro Q. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071871/
https://ncbi.nlm.nih.gov/pubmed/27762277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35449
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