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AMPylation matches BiP activity to client protein load in the endoplasmic reticulum

The endoplasmic reticulum (ER)-localized Hsp70 chaperone BiP affects protein folding homeostasis and the response to ER stress. Reversible inactivating covalent modification of BiP is believed to contribute to the balance between chaperones and unfolded ER proteins, but the nature of this modificati...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Preissler, Steffen, Rato, Cláudia, Chen, Ruming, Antrobus, Robin, Ding, Shujing, Fearnley, Ian M, Ron, David
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739761/
https://ncbi.nlm.nih.gov/pubmed/26673894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12621
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