Targeted Gene Transfer to the Brain via the Delivery of Brain-Penetrating DNA Nanoparticles with Focused Ultrasound

Gene therapy holds promise for the treatment of many pathologies of the central nervous system (CNS), including brain tumors and neurodegenerative diseases. However, the delivery of systemically administered gene carriers to the CNS is hindered by both the blood-brain barrier (BBB) and the nanoporou...

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Detaylı Bibliyografya
Yayımlandı:J Control Release
Asıl Yazarlar: Mead, Brian P., Mastorakos, Panagiotis, Suk, Jung Soo, Klibanov, Alexander L., Hanes, Justin, Price, Richard J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739627/
https://ncbi.nlm.nih.gov/pubmed/26732553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.12.034
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