Noninvasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound

The blood-brain barrier (BBB) presents a significant obstacle for the treatment of many central nervous system (CNS) disorders, including invasive brain tumors, Alzheimer’s, Parkinson’s and stroke. Therapeutics must be capable of bypassing the BBB and also penetrate the brain parenchyma to achieve a...

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Detalhes bibliográficos
Main Authors: Nance, Elizabeth, Timbie, Kelsie, Miller, G. Wilson, Song, Ji, Louttit, Cameron, Klibanov, Alexander L, Shih, Ting-Yu, Swaminathan, Ganesh, Tamargo, Rafael J., Woodworth, Graeme F., Hanes, Justin, Price, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125545/
https://ncbi.nlm.nih.gov/pubmed/24979210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.06.031
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