Noninvasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound

The blood-brain barrier (BBB) presents a significant obstacle for the treatment of many central nervous system (CNS) disorders, including invasive brain tumors, Alzheimer’s, Parkinson’s and stroke. Therapeutics must be capable of bypassing the BBB and also penetrate the brain parenchyma to achieve a...

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Bibliografiske detaljer
Main Authors: Nance, Elizabeth, Timbie, Kelsie, Miller, G. Wilson, Song, Ji, Louttit, Cameron, Klibanov, Alexander L, Shih, Ting-Yu, Swaminathan, Ganesh, Tamargo, Rafael J., Woodworth, Graeme F., Hanes, Justin, Price, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125545/
https://ncbi.nlm.nih.gov/pubmed/24979210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.06.031
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