Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Self-renewing tissue-resident macrophages are thought to be exclusively derived from embryonic progenitors. However, whether circulating monocytes can also give rise to such macrophages has not been formally investigated. Here we use a new model of diphtheria toxin-mediated depletion of liver-reside...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Scott, Charlotte L., Zheng, Fang, De Baetselier, Patrick, Martens, Liesbet, Saeys, Yvan, De Prijck, Sofie, Lippens, Saskia, Abels, Chloé, Schoonooghe, Steve, Raes, Geert, Devoogdt, Nick, Lambrecht, Bart N., Beschin, Alain, Guilliams, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737801/
https://ncbi.nlm.nih.gov/pubmed/26813785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10321
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