Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells

Peripheral tolerance is crucial for avoiding activation of self-reactive T cells to tissue-restricted antigens. Sterile tissue injury can break peripheral tolerance, but it is unclear how autoreactive T cells get activated in response to self. An example of a sterile injury is myocardial infarction...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Van der Borght, Katrien, Scott, Charlotte L., Nindl, Veronika, Bouché, Ann, Martens, Liesbet, Sichien, Dorine, Van Moorleghem, Justine, Vanheerswynghels, Manon, De Prijck, Sofie, Saeys, Yvan, Ludewig, Burkhard, Gillebert, Thierry, Guilliams, Martin, Carmeliet, Peter, Lambrecht, Bart N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379012/
https://ncbi.nlm.nih.gov/pubmed/28329691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.079
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