Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells

Autoimmune myocarditis often leads to dilated cardiomyopathy (DCM). Although T cell reactivity to cardiac self-antigen is common in the disease, it is unknown which antigen presenting cell (APC) triggers autoimmunity. Experimental autoimmune myocarditis (EAM) was induced by immunizing mice with α-my...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Van der Borght, Katrien, Scott, Charlotte L., Martens, Liesbet, Sichien, Dorine, Van Isterdael, Gert, Nindl, Veronika, Saeys, Yvan, Boon, Louis, Ludewig, Burkhard, Gillebert, Thierry C., Lambrecht, Bart N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258766/
https://ncbi.nlm.nih.gov/pubmed/30524444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02714
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