The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

Plasmacytoid dendritic cells (DCs [pDCs]) develop from pre-pDCs, whereas two lineages of conventional DCs (cDCs; cDC1s and cDC2s) develop from lineage-committed pre-cDCs. Several transcription factors (TFs) have been implicated in regulating the development of pDCs (E2-2 and Id2) and cDC1s (Irf8, Id...

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發表在:J Exp Med
Main Authors: Scott, Charlotte L., Soen, Bieke, Martens, Liesbet, Skrypek, Nicolas, Saelens, Wouter, Taminau, Joachim, Blancke, Gillian, Van Isterdael, Gert, Huylebroeck, Danny, Haigh, Jody, Saeys, Yvan, Guilliams, Martin, Lambrecht, Bart N., Berx, Geert
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2016
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886362/
https://ncbi.nlm.nih.gov/pubmed/27185854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151715
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