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The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

Plasmacytoid dendritic cells (DCs [pDCs]) develop from pre-pDCs, whereas two lineages of conventional DCs (cDCs; cDC1s and cDC2s) develop from lineage-committed pre-cDCs. Several transcription factors (TFs) have been implicated in regulating the development of pDCs (E2-2 and Id2) and cDC1s (Irf8, Id...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Scott, Charlotte L., Soen, Bieke, Martens, Liesbet, Skrypek, Nicolas, Saelens, Wouter, Taminau, Joachim, Blancke, Gillian, Van Isterdael, Gert, Huylebroeck, Danny, Haigh, Jody, Saeys, Yvan, Guilliams, Martin, Lambrecht, Bart N., Berx, Geert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886362/
https://ncbi.nlm.nih.gov/pubmed/27185854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151715
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