Functional annotation of rare gene aberration drivers of pancreatic cancer

As we enter the era of precision medicine, characterization of cancer genomes will directly influence therapeutic decisions in the clinic. Here we describe a platform enabling functionalization of rare gene mutations through their high-throughput construction, molecular barcoding and delivery to can...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tsang, Yiu Huen, Dogruluk, Turgut, Tedeschi, Philip M., Wardwell-Ozgo, Joanna, Lu, Hengyu, Espitia, Maribel, Nair, Nikitha, Minelli, Rosalba, Chong, Zechen, Chen, Fengju, Chang, Qing Edward, Dennison, Jennifer B., Dogruluk, Armel, Li, Min, Ying, Haoqiang, Bertino, Joseph R., Gingras, Marie-Claude, Ittmann, Michael, Kerrigan, John, Chen, Ken, Creighton, Chad J., Eterovic, Karina, Mills, Gordon B., Scott, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737758/
https://ncbi.nlm.nih.gov/pubmed/26806015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10500
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