Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy Against Waldenström’s Macroglobulinemia

PURPOSE: Waldenström’s macroglobulinemia (WM) is a lymphoproliferative disorder characterized by good initial responses to standard therapeutics, but only a minority of patients achieve complete remissions, and most inevitably relapse, indicating a need for novel agents. B-cell receptor signaling ha...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Kuiatse, Isere, Baladandayuthapani, Veerabhadran, Lin, Heather Y., Thomas, Sheeba K., Bjorklund, Chad C., Weber, Donna M., Wang, Michael, Shah, Jatin J., Zhang, Xing-Ding, Jones, Richard J., Ansell, Stephen M., Yang, Guang, Treon, Steven P., Orlowski, Robert Z.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737551/
https://ncbi.nlm.nih.gov/pubmed/25748087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1462
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