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Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor
Pyruvate kinase M2 (PKM2) and pyruvate dehydrogenase complex (PDC) regulate production of acetyl-CoA, which functions as an acetyl donor in diverse enzymatic reactions, including histone acetylation. However, the mechanism by which the acetyl-CoA required for histone acetylation is ensured in a gene...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737187/ https://ncbi.nlm.nih.gov/pubmed/26405201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv967 |
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