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Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin

The association and dissociation of DNA damage response (DDR) factors with damaged chromatin occurs dynamically, which is crucial for the activation of DDR signaling in a spatiotemporal manner. We previously showed that the TIP60 histone acetyltransferase complex acetylates histone H2AX, to facilita...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Cell Biol
Κύριοι συγγραφείς: Ikura, Masae, Furuya, Kanji, Matsuda, Shun, Matsuda, Ryo, Shima, Hiroki, Adachi, Jun, Matsuda, Tomonari, Shiraki, Takuma, Ikura, Tsuyoshi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648820/
https://ncbi.nlm.nih.gov/pubmed/26438602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00757-15
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