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Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks
The DNA damage checkpoint pathway is activated in response to DNA lesions and replication stress to preserve genome integrity. However, hyper-activation of this surveillance system is detrimental to the cell, because it might prevent cell cycle re-start after repair, which may also lead to senescenc...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4737138/ https://ncbi.nlm.nih.gov/pubmed/26490958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1080 |
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