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Regulation of DNA Double Strand Breaks Processing: Focus on Barriers

In all the eukaryotic cells, nucleolytic processing (resection) of a double strand DNA break (DSB) is a key step to channel the repair of the lesion toward the homologous recombination, at the expenses of the non-homologous end joining (NHEJ). The coordinated action of several nucleases and helicase...

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Détails bibliographiques
Publié dans:Front Mol Biosci
Auteurs principaux: Marini, Federica, Rawal, Chetan C., Liberi, Giordano, Pellicioli, Achille
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646425/
https://ncbi.nlm.nih.gov/pubmed/31380392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00055
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