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Slx4 Regulates DNA Damage Checkpoint-dependent Phosphorylation of the BRCT Domain Protein Rtt107/Esc4

RTT107 (ESC4, YHR154W) encodes a BRCA1 C-terminal-domain protein that is important for recovery from DNA damage during S phase. Rtt107 is a substrate of the checkpoint protein kinase Mec1, although the mechanism by which Rtt107 is targeted by Mec1 after checkpoint activation is currently unclear. Sl...

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Main Authors: Roberts, Tania M., Kobor, Michael S., Bastin-Shanower, Suzanne A., Ii, Miki, Horte, Sonja A., Gin, Jennifer W., Emili, Andrew, Rine, Jasper, Brill, Steven J., Brown, Grant W.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345688/
https://ncbi.nlm.nih.gov/pubmed/16267268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0785
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