Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Cancers contain a wide diversity of cell types that are defined by differentiation states, genetic mutations and altered epigenetic programmes that impart functional diversity to individual cells. Elevated tumour cell heterogeneity is linked with progression, therapy resistance and relapse. Yet, ima...

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Vydáno v:Nat Commun
Hlavní autoři: Tang, Qin, Moore, John C., Ignatius, Myron S., Tenente, Inês M., Hayes, Madeline N., Garcia, Elaine G., Torres Yordán, Nora, Bourque, Caitlin, He, Shuning, Blackburn, Jessica S., Look, A. Thomas, Houvras, Yariv, Langenau, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735845/
https://ncbi.nlm.nih.gov/pubmed/26790525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10358
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