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Zebrafish as a model to assess cancer heterogeneity, progression and relapse
Clonal evolution is the process by which genetic and epigenetic diversity is created within malignant tumor cells. This process culminates in a heterogeneous tumor, consisting of multiple subpopulations of cancer cells that often do not contain the same underlying mutations. Continuous selective pre...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073265/ https://ncbi.nlm.nih.gov/pubmed/24973745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.015842 |
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