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Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Cancers contain a wide diversity of cell types that are defined by differentiation states, genetic mutations and altered epigenetic programmes that impart functional diversity to individual cells. Elevated tumour cell heterogeneity is linked with progression, therapy resistance and relapse. Yet, ima...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Tang, Qin, Moore, John C., Ignatius, Myron S., Tenente, Inês M., Hayes, Madeline N., Garcia, Elaine G., Torres Yordán, Nora, Bourque, Caitlin, He, Shuning, Blackburn, Jessica S., Look, A. Thomas, Houvras, Yariv, Langenau, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735845/
https://ncbi.nlm.nih.gov/pubmed/26790525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10358
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