Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Cancers contain a wide diversity of cell types that are defined by differentiation states, genetic mutations and altered epigenetic programmes that impart functional diversity to individual cells. Elevated tumour cell heterogeneity is linked with progression, therapy resistance and relapse. Yet, ima...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tang, Qin, Moore, John C., Ignatius, Myron S., Tenente, Inês M., Hayes, Madeline N., Garcia, Elaine G., Torres Yordán, Nora, Bourque, Caitlin, He, Shuning, Blackburn, Jessica S., Look, A. Thomas, Houvras, Yariv, Langenau, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735845/
https://ncbi.nlm.nih.gov/pubmed/26790525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10358
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