Single-cell imaging of normal and malignant cell engraftment into optically clear prkdc-null SCID zebrafish

Cell transplantation into immunodeficient mice has revolutionized our understanding of regeneration, stem cell self-renewal, and cancer; yet models for direct imaging of engrafted cells has been limited. Here, we characterize zebrafish with mutations in recombination activating gene 2 (rag2), DNA-de...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Moore, John C., Tang, Qin, Yordán, Nora Torres, Moore, Finola E., Garcia, Elaine G., Lobbardi, Riadh, Ramakrishnan, Ashwin, Marvin, Dieuwke L., Anselmo, Anthony, Sadreyev, Ruslan I., Langenau, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110017/
https://ncbi.nlm.nih.gov/pubmed/27810924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160378
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