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T Cell Immune Deficiency in zap70 Mutant Zebrafish
ZAP70 [zeta-chain (TCR)-associated protein kinase, 70-kDa], is required for T cell activation. ZAP70 deficiencies in humans and null mutations in mice lead to severe combined immune deficiency. Here, we describe a zap70 loss-of-function mutation in zebrafish (zap70(y442)) that was created using tran...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108876/ https://ncbi.nlm.nih.gov/pubmed/27601584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00281-16 |
| תגים: |
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