T Cell Immune Deficiency in zap70 Mutant Zebrafish

ZAP70 [zeta-chain (TCR)-associated protein kinase, 70-kDa], is required for T cell activation. ZAP70 deficiencies in humans and null mutations in mice lead to severe combined immune deficiency. Here, we describe a zap70 loss-of-function mutation in zebrafish (zap70(y442)) that was created using tran...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Mol Cell Biol
Main Authors: Moore, John C., Mulligan, Timothy S., Yordán, Nora Torres, Castranova, Daniel, Pham, Van N., Tang, Qin, Lobbardi, Riadh, Anselmo, Anthony, Liwski, Robert S., Berman, Jason N., Sadreyev, Ruslan I., Weinstein, Brant M., Langenau, David M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108876/
https://ncbi.nlm.nih.gov/pubmed/27601584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00281-16
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla