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Optimized cell transplantation using adult rag2 mutant zebrafish
Cell transplantation into adult zebrafish has lagged behind mouse due to the lack of immune compromised models. Here, we have created homozygous rag2(E450fs) mutant zebrafish that have reduced numbers of functional T and B cells but are viable and fecund. Mutant fish engraft zebrafish muscle, blood...
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| Опубликовано в: : | Nat Methods |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294527/ https://ncbi.nlm.nih.gov/pubmed/25042784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3031 |
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