Optimized cell transplantation using adult rag2 mutant zebrafish

Cell transplantation into adult zebrafish has lagged behind mouse due to the lack of immune compromised models. Here, we have created homozygous rag2(E450fs) mutant zebrafish that have reduced numbers of functional T and B cells but are viable and fecund. Mutant fish engraft zebrafish muscle, blood...

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Publicat a:Nat Methods
Autors principals: Tang, Qin, Abdelfattah, Nouran S., Blackburn, Jessica S., Moore, John C., Martinez, Sarah A., Moore, Finola E., Lobbardi, Riadh, Tenente, Inês M., Ignatius, Myron S., Berman, Jason N., Liwski, Robert S., Houvras, Yariv, Langenau, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294527/
https://ncbi.nlm.nih.gov/pubmed/25042784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3031
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