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Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding.

The L-21 Sca I ribozyme derived from the group I intron of Tetrahymena thermophila pre-rRNA catalyzes an endonuclease reaction analogous to the first step of self-splicing. Guanosine (G) is bound by the ribozyme, and its 3'-hydroxyl group acts as the nucleophile. Here, we provide evidence that...

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Detaylı Bibliyografya
Asıl Yazarlar: McConnell, T S, Cech, T R, Herschlag, D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1993
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC47356/
https://ncbi.nlm.nih.gov/pubmed/8378306
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