The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

Treatment of Staphylococcus aureus infections has become increasingly challenging due to the rapid emergence and dissemination of methicillin-resistant strains. In addition, S. aureus reside within biofilms at the site of infection. Few novel antibacterial agents have been developed in recent years...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Brackman, Gilles, Breyne, Koen, De Rycke, Riet, Vermote, Arno, Van Nieuwerburgh, Filip, Meyer, Evelyne, Van Calenbergh, Serge, Coenye, Tom
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734334/
https://ncbi.nlm.nih.gov/pubmed/26828772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20321
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