The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

Treatment of Staphylococcus aureus infections has become increasingly challenging due to the rapid emergence and dissemination of methicillin-resistant strains. In addition, S. aureus reside within biofilms at the site of infection. Few novel antibacterial agents have been developed in recent years...

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Pubblicato in:Sci Rep
Autori principali: Brackman, Gilles, Breyne, Koen, De Rycke, Riet, Vermote, Arno, Van Nieuwerburgh, Filip, Meyer, Evelyne, Van Calenbergh, Serge, Coenye, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734334/
https://ncbi.nlm.nih.gov/pubmed/26828772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20321
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