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Comparison of Strategies for Non-perturbing Labeling of α-Synuclein to Study Amyloidogenesis
Characterization of the amyloidogenic Parkinson’s Disease protein α-synuclein (αS) has proven difficult due to its structural plasticity. Here, we present a number of complementary methods to site-specifically introduce fluorescent probes to examine αS fibril formation and cellular uptake. By using...
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Publicat a: | Org Biomol Chem |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2016
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4733880/ https://ncbi.nlm.nih.gov/pubmed/26695131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02329g |
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