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Modulating the Amyloidogenesis of α-Synuclein

Alphα-synuclein is found in the neuronal cells but its native function is not well known. While α-synuclein is an intrinsically disordered protein that adopts a helical conformation upon membrane binding, numerous studies have shown that oligomeric b-forms of this protein are cytotoxic. This respons...

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Detalhes bibliográficos
Publicado no:Curr Neuropharmacol
Main Authors: Sivanesam, Kalkena, Andersen, Niels H.
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857621/
https://ncbi.nlm.nih.gov/pubmed/26517049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X13666151030103153
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