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Modulating the Amyloidogenesis of α-Synuclein
Alphα-synuclein is found in the neuronal cells but its native function is not well known. While α-synuclein is an intrinsically disordered protein that adopts a helical conformation upon membrane binding, numerous studies have shown that oligomeric b-forms of this protein are cytotoxic. This respons...
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| Pubblicato in: | Curr Neuropharmacol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Bentham Science Publishers
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4857621/ https://ncbi.nlm.nih.gov/pubmed/26517049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X13666151030103153 |
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