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Solution Structure of the HIV-1 Intron Splicing Silencer and Its Interactions with the UP1 Domain of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A1

Splicing patterns in human immunodeficiency virus type 1 (HIV-1) are maintained through cis regulatory elements that recruit antagonistic host RNA-binding proteins. The activity of the 3′ acceptor site A7 is tightly regulated through a complex network of an intronic splicing silencer (ISS), a bipart...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jain, Niyati, Morgan, Christopher E., Rife, Brittany D., Salemi, Marco, Tolbert, Blanton S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732216/
https://ncbi.nlm.nih.gov/pubmed/26607354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674564
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