Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a multipurpose RNA-binding protein (RBP) involved in normal and pathological RNA metabolism. Transcriptome-wide mapping and in vitro evolution identify consensus hnRNP A1 binding motifs; however, such data do not reveal how surrounding RNA seq...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Jain, Niyati, Lin, Hsuan-Chun, Morgan, Christopher E., Harris, Michael E., Tolbert, Blanton S.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2017
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338530/
https://ncbi.nlm.nih.gov/pubmed/28193894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616371114
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