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HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation

Enteroviruses use a type I IRES structure to facilitate protein synthesis and promote genome replication. Type I IRES elements require auxiliary host proteins to organize RNA structure for 40S ribosomal subunit assembly. Heterogeneous nuclear ribonucleoprotein A1 stimulates Enterovirus 71 (EV71) tra...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Main Authors: Tolbert, Michele, Morgan, Christopher E., Pollum, Marvin, Crespo-Hernández, Carlos E., Li, Mei-Ling, Brewer, Gary, Tolbert, Blanton S.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610934/
https://ncbi.nlm.nih.gov/pubmed/28625847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.06.007
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