Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing

Alternative splicing of HIV-1 mRNAs increases viral coding potential and controls the levels and timing of gene expression. HIV-1 splicing is regulated in part by heterogeneous nuclear ribonucleoproteins (hnRNPs) and their viral target sequences, which typically repress splicing when studied outside...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Kutluay, Sebla B., Emery, Ann, Penumutchu, Srinivasa R., Townsend, Dana, Tenneti, Kasyap, Madison, Michaela K., Stukenbroeker, Amanda M., Powell, Chelsea, Jannain, David, Tolbert, Blanton S., Swanstrom, Ronald I., Bieniasz, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803249/
https://ncbi.nlm.nih.gov/pubmed/31413137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01048-19
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