Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing

Alternative splicing of HIV-1 mRNAs increases viral coding potential and controls the levels and timing of gene expression. HIV-1 splicing is regulated in part by heterogeneous nuclear ribonucleoproteins (hnRNPs) and their viral target sequences, which typically repress splicing when studied outside...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Kutluay, Sebla B., Emery, Ann, Penumutchu, Srinivasa R., Townsend, Dana, Tenneti, Kasyap, Madison, Michaela K., Stukenbroeker, Amanda M., Powell, Chelsea, Jannain, David, Tolbert, Blanton S., Swanstrom, Ronald I., Bieniasz, Paul D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Genome Replication and Regulation of Viral Gene Expression
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803249/
https://ncbi.nlm.nih.gov/pubmed/31413137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01048-19
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