Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells

Gene delivery into hCD34+ hematopoietic stem/progenitor cells (HSPCs) using human immunodeficiency virus, type 1-derived lentiviral vectors (LVs) has several promising therapeutic applications. Numerous clinical trials are currently underway. However, the efficiency, safety, and cost of LV gene ther...

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Vydáno v:J Biol Chem
Hlavní autoři: Majdoul, Saliha, Seye, Ababacar K., Kichler, Antoine, Holic, Nathalie, Galy, Anne, Bechinger, Burkhard, Fenard, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732202/
https://ncbi.nlm.nih.gov/pubmed/26668323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675033
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