Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes

Ex vivo transduction of human CD34(+) hematopoietic stem/progenitor cells (hCD34(+) HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results. So far, several enhancers have been used to improve this process. Among them, Retronecti...

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Publicat a:Mol Ther Methods Clin Dev
Autors principals: Piovan, Claudia, Marin, Virna, Scavullo, Cinzia, Corna, Stefano, Giuliani, Erica, Bossi, Sergio, Galy, Anne, Fenard, David, Bordignon, Claudio, Rizzardi, Gian Paolo, Bovolenta, Chiara
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415310/
https://ncbi.nlm.nih.gov/pubmed/28480301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.02.003
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