טוען...
Covalent targeting of acquired cysteines in cancer
The thiolate side chain of cysteine has a unique functionality that drug hunters and chemical biologists have begun to exploit. For example, targeting cysteine residues in the ATP-binding pockets of kinases with thiol-reactive molecules has afforded increased selectivity and potency to drugs like im...
שמור ב:
| הוצא לאור ב: | Curr Opin Chem Biol |
|---|---|
| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731306/ https://ncbi.nlm.nih.gov/pubmed/26629855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.11.004 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|