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Synthetic Isoprenoid Analogues for the Study of Prenylated Proteins: Fluorescent Imaging and Proteomic Applications

Protein prenylation is a posttranslational modification catalyzed by prenyltransferases involving the attachment of farnesyl or geranylgeranyl groups to residues near the C-termini of proteins. This irreversible covalent modification is important for membrane localization and proper signal transduct...

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Bibliographic Details
Published in:Bioorg Chem
Main Authors: Wang, Yen-Chih, Distefano, Mark D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731301/
https://ncbi.nlm.nih.gov/pubmed/26709869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2015.12.003
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