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Molecular Combing of Single DNA Molecules on the 10 Megabase Scale

DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fi...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Kaykov, Atanas, Taillefumier, Thibaud, Bensimon, Aaron, Nurse, Paul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726065/
https://ncbi.nlm.nih.gov/pubmed/26781994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19636
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