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Molecular Combing of Single DNA Molecules on the 10 Megabase Scale

DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fi...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Kaykov, Atanas, Taillefumier, Thibaud, Bensimon, Aaron, Nurse, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726065/
https://ncbi.nlm.nih.gov/pubmed/26781994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19636
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