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Molecular Combing of Single DNA Molecules on the 10 Megabase Scale
DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fi...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4726065/ https://ncbi.nlm.nih.gov/pubmed/26781994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19636 |
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