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Molecular Combing of Single DNA Molecules on the 10 Megabase Scale

DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200–500 kb. We have improved the DNA combing procedure so that DNA molecules can be analysed up to the length of entire chromosomes in fi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kaykov, Atanas, Taillefumier, Thibaud, Bensimon, Aaron, Nurse, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726065/
https://ncbi.nlm.nih.gov/pubmed/26781994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19636
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